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A phenol with diverse biological activities; scavenges DPPH and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM, respectively); reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings from 1-100 µM; inhibits morpholine- and sodium nitrite-induced adenocarcinoma formation in mice at 21.8 g/kg; inhibits passive cutaneous anaphylaxis in mice at 50 mg/kg
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A phenol with diverse biological activities; scavenges DPPH and hydroxyl radicals in cell-free assays (IC50s = 9.4 and 191 µM, respectively); reverses abscisic acid-induced inhibition of hypocotyl growth in A. caudatus seedlings from 1-100 µM; inhibits morpholine- and sodium nitrite-induced adenocarcinoma formation in mice at 21.8 g/kg; inhibits passive cutaneous anaphylaxis in mice at 50 mg/kg
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An ω-alkyne derivative of docosahexaenoic acid; can be joined with azide-containing molecules using click chemistry; can be used track fatty acid metabolism in cells via click chemistry linkage to fluorophores
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A CPT1 inhibitor and an active metabolite of oxfenicine; inhibits CPT1 in isolated rat liver mitochondria from 200 to 1,000 µM; inhibits oleate oxidation in isolated rat hepatocytes
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A naturally occurring fatty acid methyl ester; has been found in the cuticular wax of P. abies needles; has been found in sediment samples from the Harney River in Florida and Lake Kivu in the EAst African rift valley
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γ-Linolenic acid is an ω-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. γ-Linolenic acid produces 53% inhibition at a 1 mg/kg dose in an in vivo model of LTB4-induced bronchoconstriction.{2361}
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A glycine-conjugated form of chenodeoxycholic acid; reduces formation of cholic acid in primary human hepatocytes at 100 µM; reduces the number LC3 puncta and is cytotoxic to L-02 hepatocytes at 50, 75, and 100 µM; induces apoptosis in isolated rat hepatocytes at 50 µM; fecal levels are decreased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet
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An isotopically enriched form of a PUFA with carbon-13 occurring at positions 1, 2, 3, 4, and 5; used to study metabolic processes related to arachidonic acid by means of mass spectrometry
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